INGREDIENT SCIENCE

At the heart of our PowerCell PrO range lies a commitment to delivering formulations that are backed by science and our extensive decades-long research. Each ingredient we use is selected not only for its potency but also for its foundation in evidence-based research. This page highlights the scientific validation of our raw materials, ensuring that every component in our products contributes meaningfully to supporting health and wellness.

Our formulations are grounded in scientific foundations, focusing on the science behind our ingredients to enhance bioavailability, improve cellular function, and align with the body's natural energy systems. Below, you’ll find research and evidence, including white papers and studies, demonstrating the rationale for the inclusion of each ingredient in our products.

Explore the raw material research below to see how our evidence-based approach ensures the highest efficacy and integrity in our products.

Here are some scientific studies and articles that provide evidence supporting the efficacy of key ingredients in our PowerCell PrO products:

1. Nicotinamide Mononucleotide (NMN)

• "Recent research into nicotinamide mononucleotide and ageing"

This article discusses how NMN serves as a precursor to NAD+, essential for various critical cell functions, including metabolism and DNA repair.

• "Advances in the Synthesis and Physiological Metabolic Regulation of Nicotinamide Mononucleotide"

Nicotinamide mononucleotide (NMN), the direct precursor of nicotinamide adenine dinucleotide (NAD⁺), is involved in the regulation of many physiological and metabolic reactions in the body. NMN can indirectly affect cellular metabolic pathways, DNA repair, and senescence, while also being essential for maintaining tissues and dynamic metabolic equilibria, pro"moting healthy aging. 

•  "Advancements in NMN biotherapy and research updates in the field of digestive system diseases"

This review highlights NMN's role in energy metabolism, cellular aging, and DNA repair, emphasizing its therapeutic potential.  

• "Nicotinamide mononucleotide impacts HIV-1 infection by modulating immune activation in T lymphocytes and humanized mice"

Using multiple infection models, we found that NMN treatment suppressed viral production in HIV-1-infected ACH-2 and primary CD4⁺ T cells at the post-transcription stage. On the one hand, NMN treatment preferentially decreased the intracellular HIV-1 p24 production in CD25⁺CD4⁺ T cells. On the other hand, NMN inhibited the expression of late T cell activation markers including CD25 and HLA-DR consistently using in vitro, ex vivo, and in vivo models. Furthermore, NMN improved the therapeutic efficacy of cART in HIV-1-infected humanized mice by improving the CD4⁺ T cell reconstitution. (The Lancet, Volume 98, December 2023).

2. Organic Spirulina

• "Beneficial Effects of Spirulina Supplementation in the Management of Cardiovascular Diseases"
  This study explores how minerals in Spirulina, including those similar to montmorillonite, support cardiovascular health and may influence mitochondrial function.
• "Spirulina Promotes Stem Cell Genesis and Protects against LPS Induced Declines in Neurogenesis in Vitro"
  This research indicates that Spirulina, rich in phycocyanin, promotes stem cell genesis and offers neuroprotective benefits.
• "The antioxidant, immunomodulatory, and anti-inflammatory activities of Spirulina: an overview"
  This comprehensive review explores Spirulina's health benefits, including its high protein and vitamin content, and its potential in combating oxidative stress and dysfunctional immunity. 
• "Spirulina platensis prevents high glucose-induced oxidative stress mitochondrial damage mediated apoptosis in cardiomyoblasts"
  This study examines Spirulina's protective effects against oxidative stress and mitochondrial dysfunction in heart cells.

2. Chlorella

• "Potential of Chlorella as a Dietary Supplement to Promote Human Health"

Chlorella is a green unicellular alga that is commercially produced and distributed worldwide as a dietary supplement. Chlorella products contain numerous nutrients and vitamins, including D and B₁₂, that are absent in plant-derived food sources. Chlorella contains larger amounts of folate and iron than other plant-derived foods. Chlorella supplementation to mammals, including humans, has been reported to exhibit various pharmacological activities, including immunomodulatory, antioxidant, antidiabetic, antihypertensive, and antihyperlipidemic activities. "

• "Edible Algae and their Bioactive Compounds in the Prevention and Treatment of Metabolic Alteration"

Marine and freshwater algae and their products are in growing demand worldwide because of their nutritional and functional properties. Microalgae (unicellular algae) will constitute one of the major foods of the future for nutritional and environmental reasons. They are sources of high-quality protein and bioactive molecules with potential application in the modern epidemics of obesity and diabetes. They may also contribute decisively to sustainability through carbon dioxide fixation and minimization of agricultural land use. 

3. Phycocyanin

• "Phycocyanin: A Potential Drug for Cancer Treatment"

Phycocyanin isolated from marine organisms has the characteristics of high efficiency and low toxicity, and it can be used as a functional food. It has been reported that phycocyanin has anti-oxidative function, anti-inflammatory activity, anti-cancer function, immune enhancement function, liver and kidney protection pharmacological effects. Thus, phycocyanin has an important development and utilization as a potential drug, and phycocyanin has become a new hot spot in the field of drug research. 

• "Exploring the Benefits of Phycocyanin"

Large-scale production of microalgae and their bioactive compounds has steadily increased in response to global demand for natural compounds. Spirulina, in particular, has been used due to its high nutritional value, especially its high protein content. Promising biological functions have been associated with Spirulina extracts, mainly related to its high value added blue pigment, phycocyanin. Phycocyanin is used in several industries such as food, cosmetics, and pharmaceuticals, which increases its market value.

4. Chlorophyllin

• "Chlorophyllin intervention reduces aflatoxin–DNA adducts in individuals at high risk for liver cancer"

Chlorophyllin, a mixture of semisynthetic, water-soluble derivatives of chlorophyll that is used as a food colorant and over-the-counter medicine, has been shown to be an effective inhibitor of aflatoxin hepatocarcinogenesis in animal models by blocking carcinogen bioavailability.

5. Chlorella Growth Factors

• "Chlorella growth factor extraction and its effect on gene expression of types I and III collagen in skin fibroblast cells."

Using quantitative PCR it was confirmed that CGF increased I and II collagens in human fibroblast cells.

6. Silica (as Silicon Dioxide)

• "Silicon: the health benefits of a metalloid"

Collectively, the food supply contributes enough silicon in the forms aforementioned that could be absorbed and significantly improve overall human health despite the negative perception of silica as a health hazard. This review discusses the possible biological potential of the metalloid silicon as bioavailable orthosilicic acid and the potential beneficial effects on human health.

7. Montmorillonite Minerals

•  "Bentonite Clay as a Natural Remedy"

Its other name, Montmorillonite clay, stems from the region of France called Montmorillon, where it was first found. It has been used and eaten from ancient time till now as human believes in its therapeutic benefits. When it is mixed with water a paste is formed which has been used both externally and internally.

• Efficacy of Organo-Modified Nano Montmorillonite to Protect against the Cumulative Health Risk of Aflatoxin B1 and Ochratoxin A in Rats"

This study evaluates the protective effects of nano montmorillonite against specific toxins, highlighting its potential in detoxification and health risk mitigation.

• "An Overview of Medical Applications of Montmorillonite Clay"
  This review provides insights into the various medical applications of montmorillonite clay, emphasizing its role in detoxification and potential health benefits.

8. Gold

• "Application of Gold in Biomedicine: Past, Present and Future"

Existing knowledge is helpful to drive the research for future applications of gold compounds. Examples have demonstrated in traditional medicine for providing clues. The anti-inflammatory properties of gold compounds used for treatment of rheumatoid arthritis may also exist in FANCs.

• "Gold-based therapy: From past to present"

Although by no means exhaustive, these studies provide a scientific foundation for the inclusion of these ingredients in our formulations, demonstrating their potential roles in supporting mitochondrial function and enhancing cellular energy.

By basing our formulations on scientific validation and incorporating only evidence-based ingredients, we ensure that every product in the PowerCell PrO range delivers meaningful benefits to your health. If you'd like to learn more about the research behind any specific ingredient, feel free to contact us.